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Literature summary extracted from

  • Mengin-Lecreulx, D.; van Heijenoort, J.; Park, J.T.
    Identification of the mpl gene encoding UDP-N-acetylmuramate:L-alanyl-gamma-glutamyl-meso-diaminopimelate ligase in Escherichia coli and its role in recycling of cell wall peptidoglycan (1996), J. Bacteriol., 178, 5347-5352.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.3.2.13
-
 Escherichia coli
6.3.2.45 expressed under control of the trc promoter Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.2.13 ATP + UDP-N-MurNAc-L-Ala-D-Glu + meso-2,6-diaminoheptanedioate Escherichia coli enzyme is not essential for growth ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.13 Escherichia coli
-
-
-
6.3.2.45 Escherichia coli P37773
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.13 ATP + UDP-MurNAc-L-Ala-D-Glu + meso-2,6-diaminoheptanedioate
-
 Escherichia coli ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate
-
 ?
6.3.2.13 ATP + UDP-N-MurNAc-L-Ala-D-Glu + meso-2,6-diaminoheptanedioate enzyme is not essential for growth Escherichia coli ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.3.2.45 UDP-MurNAc:L-Ala-gamma-D-Glu-meso-A2pm ligase
-
 Escherichia coli
6.3.2.45 yjfG
-
 Escherichia coli

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
6.3.2.45 37
-
 assay at Escherichia coli

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.3.2.45 8.6
-
 assay at Escherichia coli

General Information

EC Number General Information Comment Organism
6.3.2.45 malfunction a null mutant totally lacking activity is viable, showing that the enzyme is not essential for growth Escherichia coli