BRENDA - Enzyme Database
show all sequences of 7.4.2.9

Peptide transport and chemotaxis in Escherichia coli and Salmonella typhimurium characterization of the dipeptide permease (Dpp) and the dipeptide-binding protein

Abouhamad, W.; Manson, M.; Gibson, M.; Higgins, C.; Mol. Microbiol. 5, 1035-1047 (1991) View publication on PubMed

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
periplasm
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
periplasm
-
Escherichia coli
-
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
ATP + H2O + a dipeptide-[dipeptide-binding protein][side 1]
Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + phosphate + a dipeptide[side 2] + [dipeptide-binding protein][side 1]
-
-
?
ATP + H2O + a dipeptide-[dipeptide-binding protein][side 1]
Escherichia coli
-
ADP + phosphate + a dipeptide[side 2] + [dipeptide-binding protein][side 1]
-
-
?
Organism
Organism
UniProt
Commentary
Textmining
Escherichia coli
-
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
ATP + H2O + a dipeptide-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + a dipeptide[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + a dipeptide-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + a dipeptide[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + Gly-L-His-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + Gly-L-His[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + Gly-L-His-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + Gly-L-His[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + Gly-L-Leu-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + Gly-L-Leu[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + Gly-L-Leu-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + Gly-L-Leu[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-His-L-Ala[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + L-His-L-Ala[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-His-L-Ala[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + L-His-L-Ala[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Leu-Gly-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + L-Leu-Gly[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Leu-Gly-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + L-Leu-Gly[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Leu-L-Val-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + L-Leu-L-Val[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Leu-L-Val-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + L-Leu-L-Val[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Pro-Gly-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + L-Pro-Gly[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Pro-Gly-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + L-Pro-Gly[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Pro-L-Val-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + L-Pro-L-Val[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Pro-L-Val-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + L-Pro-L-Val[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
Synonyms
Synonyms
Commentary
Organism
dipeptide permease
-
Salmonella enterica subsp. enterica serovar Typhimurium
dipeptide permease
-
Escherichia coli
DPP
-
Salmonella enterica subsp. enterica serovar Typhimurium
DPP
-
Escherichia coli
DppA
-
Salmonella enterica subsp. enterica serovar Typhimurium
DppA
-
Escherichia coli
DppA
the gene encodes a periplasmic dipeptide-binding protein required for dipeptide transport and chemotaxis
Salmonella enterica subsp. enterica serovar Typhimurium
DppA
the gene encodes a periplasmic dipeptide-binding protein required for dipeptide transport and chemotaxis
Escherichia coli
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
periplasm
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
periplasm
-
Escherichia coli
-
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
ATP + H2O + a dipeptide-[dipeptide-binding protein][side 1]
Salmonella enterica subsp. enterica serovar Typhimurium
-
ADP + phosphate + a dipeptide[side 2] + [dipeptide-binding protein][side 1]
-
-
?
ATP + H2O + a dipeptide-[dipeptide-binding protein][side 1]
Escherichia coli
-
ADP + phosphate + a dipeptide[side 2] + [dipeptide-binding protein][side 1]
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
ATP + H2O + a dipeptide-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + a dipeptide[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + a dipeptide-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + a dipeptide[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + Gly-L-His-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + Gly-L-His[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + Gly-L-His-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + Gly-L-His[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + Gly-L-Leu-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + Gly-L-Leu[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + Gly-L-Leu-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + Gly-L-Leu[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-His-L-Ala[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + L-His-L-Ala[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-His-L-Ala[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + L-His-L-Ala[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Leu-Gly-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + L-Leu-Gly[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Leu-Gly-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + L-Leu-Gly[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Leu-L-Val-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + L-Leu-L-Val[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Leu-L-Val-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + L-Leu-L-Val[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Pro-Gly-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + L-Pro-Gly[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Pro-Gly-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + L-Pro-Gly[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Pro-L-Val-[dipeptide-binding protein][side 1]
-
751591
Salmonella enterica subsp. enterica serovar Typhimurium
ADP + phosphate + L-Pro-L-Val[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
ATP + H2O + L-Pro-L-Val-[dipeptide-binding protein][side 1]
-
751591
Escherichia coli
ADP + phosphate + L-Pro-L-Val[side 2] + [dipeptide-binding protein][side 1]
-
-
-
?
Other publictions for EC 7.4.2.9
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
749669
Kuenzl
Mutant variants of the substr ...
Escherichia coli
Appl. Environ. Microbiol.
84
e00340-18
2018
-
-
1
-
-
-
-
2
1
-
-
1
-
3
-
-
1
-
-
-
-
-
5
-
2
-
-
1
2
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
1
-
-
1
-
-
-
1
-
-
-
-
5
-
-
-
1
2
-
-
-
-
-
1
1
-
2
2
751487
Asai
Characterization of a novel p ...
Treponema denticola, Treponema denticola ATCC 35405
Microb. Pathog.
123
467-472
2018
-
-
-
-
-
-
-
-
-
-
-
10
-
11
-
-
-
-
-
-
-
-
10
-
35
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
10
-
-
-
-
-
-
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
751992
Pletzer
High-throughput screening of ...
Pseudomonas aeruginosa
PLoS ONE
9
e111311
2014
-
-
-
-
-
-
-
-
1
-
-
2
-
8
-
-
-
-
-
-
-
-
14
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
14
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
749487
Li
Structure of the nucleotide-b ...
Caldanaerobacter subterraneus subsp. tengcongensis
Acta Crystallogr. Sect. D
69
256-265
2013
-
-
1
1
-
-
-
-
-
1
-
1
-
4
-
-
1
-
-
-
-
-
1
-
4
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
1
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
750952
Weinberg
Peptide transport in Helicoba ...
Helicobacter pylori, Helicobacter pylori 43504
J. Bacteriol.
189
3392-3402
2007
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
16
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
16
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
752025
Letoffe
The housekeeping dipeptide pe ...
Escherichia coli
Proc. Natl. Acad. Sci. USA
103
12891-12896
2006
-
-
-
-
-
-
-
-
1
-
-
2
-
7
-
-
-
-
-
-
-
-
6
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
749752
Sanz
Genetic and functional charac ...
Lactococcus lactis subsp. cremoris
Arch. Microbiol.
175
334-343
2001
-
-
-
-
-
-
-
-
-
-
-
1
-
4
-
-
-
-
-
-
-
-
8
1
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
8
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
751589
Elferink
Sugar transport in Sulfolobus ...
Saccharolobus solfataricus
Mol. Microbiol.
39
1494-1503
2001
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
751588
Podbielski
The group A streptococcal dip ...
Streptococcus pyogenes
Mol. Microbiol.
28
1323-1334
1998
-
-
-
-
-
-
-
-
-
-
-
5
-
5
-
-
-
-
-
-
-
-
5
-
15
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
5
5
5
5
-
-
751591
Abouhamad
Peptide transport and chemota ...
Escherichia coli, Salmonella enterica subsp. enterica serovar Typhimurium
Mol. Microbiol.
5
1035-1047
1991
-
-
-
-
-
-
-
-
2
-
-
2
-
2
-
-
-
-
-
-
-
-
16
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
16
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-