Protein Variants | Comment | Organism |
---|---|---|
E20D | mutant is not affected by the bulk pH in the range tested, no dramatic change in IC50 value for peptides Gly-Lys, beta-Ala-Lys | Escherichia coli |
E20Q | mutant is not affected by the bulk pH in the range tested, no dramatic change in IC50 value for peptides Gly-Lys, beta-Ala-Lys | Escherichia coli |
E388D | increase in IC50 value for peptides Gly-Lys, beta-Ala-Lys, increase in pH-optimum | Escherichia coli |
E388Q | increase in IC50 value for peptides Gly-Lys, beta-Ala-Lys, increase in pH-optimum | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-(gamma-aminobutanoyl)-Lys | - |
Escherichia coli | |
acetyl-Lys | - |
Escherichia coli | |
beta-Ala-Lys | - |
Escherichia coli | |
Gly-Lys | - |
Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P39276 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
dipeptide permease | - |
Escherichia coli |
tripeptide permease | - |
Escherichia coli |
Yjdl | - |
Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
wild-type | Escherichia coli |
7 | 7.5 | mutants E388D, E388Q | Escherichia coli |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
additional information | - |
IC50 value range between 0.1 and 1 mM for wild-type and E20-mutants, and increase to about 2 mM for mutant E388Q, pH not specified in the publication, temperature not specified in the publication | Escherichia coli | Gly-Lys | |
additional information | - |
IC50 value range between 0.1 and 1 mM for wild-type and E20-mutants, and increase to above 10 mM for mutant E388Q, pH not specified in the publication, temperature not specified in the publication | Escherichia coli | beta-Ala-Lys |