Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | Escherichia coli | ATP hydrolysis by SecA is required only if periplasmic loops larger than 30 amino acids have to be translocated. The signal recognition particle-dependent and SecA-dependent multiple spanning membrane protein YidC becomes SecA-independent if the large periplasmic loop connecting transmembrane domains 1 and 2 is reduced to less than 30 amino acids. The SecA dependence of a bacterial membrane protein is not solely determined by the length of the periplasmic loop but also by the presence of a down-stream TM domain | ADP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O | ATP hydrolysis by SecA is required only if periplasmic loops larger than 30 amino acids have to be translocated. The signal recognition particle-dependent and SecA-dependent multiple spanning membrane protein YidC becomes SecA-independent if the large periplasmic loop connecting transmembrane domains 1 and 2 is reduced to less than 30 amino acids. The SecA dependence of a bacterial membrane protein is not solely determined by the length of the periplasmic loop but also by the presence of a down-stream TM domain | Escherichia coli | ADP + phosphate | - |
? |