Crystallization (Comment) | Organism |
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catalytic subunit of the ATP-dependent arsenite pump is encoded by the Escherichia coli plasmid R773 | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + arsenite/in | Escherichia coli | detoxifying system | ADP + phosphate + arsenite/out | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
from plasmid R773 | - |
Purification (Comment) | Organism |
---|---|
- |
Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + arsenite/in | - |
Escherichia coli | ADP + phosphate + arsenite/out | - |
? | |
ATP + H2O + arsenite/in | detoxifying system | Escherichia coli | ADP + phosphate + arsenite/out | - |
? | |
additional information | the ArsA protein is a membrane associated ATPase, energizing the arsenite efflux pump by ATP hydrolysis, ArsA is attached to the ArsB inner-membrane protein. The ArsB protein can function alone as a chemiosmotic, membrane-potential driven arsenite-efflux transporter or together with ArsA as an ATP-driven primary membrane pump. ArsC converts the less toxic arsenate to more toxic arsenite, the substrate for the ArsB transport protein | Escherichia coli | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | the ArsA protein is a membrane associated ATPase, energizing the arsenite efflux pump by ATP hydrolysis, ArsA is attached to the ArsB inner-membrane protein. The ArsB protein can function alone as a chemiosmotic, membrane-potential driven arsenite-efflux transporter or together with ArsA as an ATP-driven primary membrane pump. ArsC reduces loss toxic arsenate to more toxic arsenite, the substrate for the ArsB transport protein | Escherichia coli |