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Literature summary for 7.2.2.19 extracted from

  • Li, J.; Codina, J.; Petroske, E.; Werle, M.J.; Willingham, M.C.; DuBose, T.D.
    The effect of beta-subunit assembly on function and localization of the colonic H+,K+-ATPase alpha-subunit (2004), Kidney Int., 66, 1068-1075.
    View publication on PubMed
Search for more literature for 7.2.2.19

Application

Application Comment Organism
additional information Na+,K+-ATPase is likely to represent the most physiologic and efficient subunit for H+,K+-ATPase alpha subunit assembly in distal colon Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
into pcDNA3.1(+)-Neo, cotransfection of HEK-293 cells with H+,K+-ATPase alpha subunit plus Na+,K+-ATPase beta1 subunit or beta3 subunit, respectively Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
Ouabain inhibits Rb+ uptake in a dose-dependent manner Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
apical plasma membrane
-
 Rattus norvegicus 16324
-

Metals/Ions

Metals/Ions Comment Organism Structure
Rb+ uptake supported by both H+,K+-ATPase alpha subunit-Na+,K+-ATPase beta1 subunit complex or beta3 subunit complex, respectively, higher uptake in cells with H+,K+-ATPase alpha subunit-Na+,K+-ATPase beta1 subunit complex Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colon distal end Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
H+,K+-ATPase
-
 Rattus norvegicus