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Literature summary for 7.2.2.14 extracted from

  • Retamal, P.; Castillo-Ruiz, M.; Mora, G.C.
    Characterization of MgtC, a virulence factor of Salmonella enterica Serovar Typhi (2009), PLoS ONE, 4, e5551.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.2.2.14

Activating Compound

Activating Compound Comment Organism Structure
additional information low Mg2+ concentration, acidic media and the PhoP regulator induce mgtC expression in Salmonella enterica serovar Typhi Salmonella enterica

Cloned(Commentary)

Cloned (Comment) Organism
gene mgtC is encoded in the pathogenicity island 3, SPI-3 Salmonella enterica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Mg2+/out Salmonella enterica the MgtC is a virulence factor in Salmonella Typhimurium that is required for growth at low Mg2+ concentrations and intramacrophage survival ADP + phosphate + Mg2+/in
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 ?

Organism

Organism UniProt Comment Textmining
Salmonella enterica
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 serovar Typhi, a Chilean clinical isolate of the human specific pathogen
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Mg2+/out
-
 Salmonella enterica ADP + phosphate + Mg2+/in
-
 ?
ATP + H2O + Mg2+/out the MgtC is a virulence factor in Salmonella Typhimurium that is required for growth at low Mg2+ concentrations and intramacrophage survival Salmonella enterica ADP + phosphate + Mg2+/in
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 ?

Subunits

Subunits Comment Organism
More MgtC epitope tagging, overview Salmonella enterica

Synonyms

Synonyms Comment Organism
MgtC
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 Salmonella enterica

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Salmonella enterica