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Literature summary for 7.2.2.13 extracted from

  • Sepp, M.; Sokolova, N.; Jugai, S.; Mandel, M.; Peterson, P.; Vendelin, M.
    Tight coupling of Na+/K+-ATPase with glycolysis demonstrated in permeabilized rat cardiomyocytes (2014), PLoS ONE, 9, e99413.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.2.2.13

Inhibitors

Inhibitors Comment Organism Structure
Ouabain about 30% inhibition at 2 mM Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Na+/in + K+/out Rattus norvegicus
-
 ADP + phosphate + Na+/out + K+/in
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cardiomyocyte
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Na+/in + K+/out
-
 Rattus norvegicus ADP + phosphate + Na+/out + K+/in
-
 ?

Synonyms

Synonyms Comment Organism
Na+/K+-ATPase
-
 Rattus norvegicus
NKA
-
 Rattus norvegicus

General Information

General Information Comment Organism
metabolism the enzyme is tightly coupled to glycolysis with undetectable flux of ATP between mitochondria and the enzyme Rattus norvegicus