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Literature summary for 7.1.2.1 extracted from

  • Serrano, R.; Kielland-Brandt, M.C.; Fink, G.R.
    Yeast plasma membrane ATPase is essential for growth and has homology with (Na+ + K+)-, K+- and Ca2+-ATPase (1986), Nature, 319, 689-593.
    View publication on PubMed
Search for more literature for 7.1.2.1

Cloned(Commentary)

Cloned (Comment) Organism
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 Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
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 Saccharomyces cerevisiae 5886
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + H+/in Saccharomyces cerevisiae the PMA1 gene encoding plasma membrane ATPase is essential because a null mutation is lethal in haploid cells. The proton gradient generated by the enzyme drives the active transport of nutrients by H+-symport. In addition, the external acidification in plants and the internal alkalinization in fungi both resulting from activation of the H+ pump, have been proposed to mediate growth responses ADP + phosphate + H+/out
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 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + H+/in
-
 Saccharomyces cerevisiae ADP + phosphate + H+/out
-
 ?
ATP + H2O + H+/in the PMA1 gene encoding plasma membrane ATPase is essential because a null mutation is lethal in haploid cells. The proton gradient generated by the enzyme drives the active transport of nutrients by H+-symport. In addition, the external acidification in plants and the internal alkalinization in fungi both resulting from activation of the H+ pump, have been proposed to mediate growth responses Saccharomyces cerevisiae ADP + phosphate + H+/out
-
 ?