Any feedback?
Literature summary for 6.3.1.13 extracted from
- Dequalinium, a new inhibitor of Mycobacterium tuberculosis mycothiol ligase identified by high-throughput screening (2009), J. Biomol. Screen., 14, 643-652.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| dequalinium chloride | ATP-competitive inhibitor of MshC, binds MshC with a KD of 0.22 microM, and inhibits the growth of Mycobacterium tuberculosis under aerobic and anaerobic conditions with minimum inhibitory and anaerobic bactericidal concentrations of 1.2 and 0.3 microg/ml, respectively | Mycobacterium tuberculosis |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mycobacterium tuberculosis | - |
- |
- |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.024 | - |
pH 8.0, 22°C | Mycobacterium tuberculosis | dequalinium | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
