Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A31N-ts20 cell | mouse embryo fibroblast cell, thermosensitive for ubiquitin-activating enzyme E1 | Mus musculus | - |
Synonyms | Comment | Organism |
---|---|---|
E1 ubiquitin-activating enzyme | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | in mouse embryo fibroblast cell A31N-ts20, which is thermosensitive for ubiquitin-activating enzyme E1, the enzymatic activity of the enzyme is heat-inactivatable in vitro; and a major mechanism responsible for E1 inactivation in vivo consists of accelerated destruction. In vivo, ubiquitination of the various protein substrates in A31N-ts20 cells requires different amounts of E1 enzyme | Mus musculus |