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Literature summary for 6.2.1.16 extracted from

  • Sato, H.; Takahashi, N.; Nakamoto, M.; Ohgami, M.; Yamazaki, M.; Fukui, T.
    Effects of streptozotocin-induced diabetes on acetoacetyl-CoA synthetase activity in rats (2002), Biochem. Pharmacol., 63, 1851-1855.
    View publication on PubMed
Search for more literature for 6.2.1.16

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 female, Sprague-Dawley strain
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Rattus norvegicus Sprague-Dawley
-
 female, Sprague-Dawley strain
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 streptozotocin-induced diabetes results in a decrease in acetoacetyl-CoA synthetase specific activity in rat liver, but not in other acetoacetyl-CoA synthetase containing tissues, e.g kidney, lung or brain, hepatic acetoacetyl-CoA synthetase activity is 8fold higher in rats fed with cholestyramine and pravastatin Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + acetoacetate + CoA
-
 Rattus norvegicus AMP + diphosphate + acetoacetyl-CoA
-
 ?
ATP + acetoacetate + CoA
-
 Rattus norvegicus Sprague-Dawley AMP + diphosphate + acetoacetyl-CoA
-
 ?