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Literature summary for 5.6.2.3 extracted from

  • Zhang, S.; Wei, T.; Hou, G.; Zhang, C.; Liang, P.; Ni, J.; Sheng, D.; Shen, Y.
    Archaeal DNA helicase HerA interacts with Mre11 homologue and unwinds blunt-ended double-stranded DNA and recombination intermediates (2008), DNA Repair, 7, 380-391.
    View publication on PubMed
Search for more literature for 5.6.2.3

Activating Compound

Activating Compound Comment Organism Structure
dsDNA ATPase activity of StoHerA is stimulated by ssDNA and dsDNA Sulfurisphaera tokodaii
repair proteins Mre11 stimulates helicase activity Sulfurisphaera tokodaii
ssDNA ATPase activity of StoHerA is stimulated by ssDNA and dsDNA Sulfurisphaera tokodaii

Cloned(Commentary)

Cloned (Comment) Organism
-
 Sulfurisphaera tokodaii

Protein Variants

Protein Variants Comment Organism
E355A mutation results in loss of ATPase and DNA helicase activities, and also dsDNA-binding ability, indicating that this residue is involved in the coupling of ATP hydrolysis, dsDNA-binding, and helicase activities Sulfurisphaera tokodaii

Organism

Organism UniProt Comment Textmining
Sulfurisphaera tokodaii Q96YR7
-
-
Sulfurisphaera tokodaii 7 Q96YR7
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Sulfurisphaera tokodaii

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O the enzyme unwinds Holliday junction, splayed-armDNA, aswell as 5'- or 3'-overhang with high efficiency Sulfurisphaera tokodaii ADP + phosphate
-
 ?
ATP + H2O the enzyme unwinds Holliday junction, splayed-armDNA, aswell as 5'- or 3'-overhang with high efficiency Sulfurisphaera tokodaii 7 ADP + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
HerA
-
 Sulfurisphaera tokodaii

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 assay at Sulfurisphaera tokodaii