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Literature summary for 5.6.2.1 extracted from

  • D'Alfonso, A.; Di Felice, F.; Carlini, V.; Wright, C.M.; Hertz, M.I.; Bjornsti, M.A.; Camilloni, G.
    Molecular mechanism of DNA topoisomerase I-dependent rDNA silencing Sir2p recruitment at ribosomal genes (2016), J. Mol. Biol., 428, 4905-4916 .
    View publication on PubMed
Search for more literature for 5.6.2.1

Protein Variants

Protein Variants Comment Organism
Y727F catalytically inactive Saccharomyces cerevisiae
Y727F catalytically inactive Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
camptothecin
-
 Homo sapiens
camptothecin
-
 Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Homo sapiens P11387
-
-
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae W303-1A
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme recruits Sir2p to the rDNA Saccharomyces cerevisiae ?
-
 ?
additional information the enzyme recruits Sir2p to the rDNA Homo sapiens ?
-
 ?
additional information the enzyme recruits Sir2p to the rDNA Saccharomyces cerevisiae W303-1A ?
-
 ?

Synonyms

Synonyms Comment Organism
DNA topoisomerase I
-
 Saccharomyces cerevisiae
DNA topoisomerase I
-
 Homo sapiens
Top1
-
 Saccharomyces cerevisiae
Top1
-
 Homo sapiens
Top1p
-
 Saccharomyces cerevisiae
Top1p
-
 Homo sapiens