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Literature summary for 5.6.2.1 extracted from

  • Goswami, A.; Qiu, S.; Dexheimer, T.S.; Ranganathan, P.; Burikhanov, R.; Pommier, Y.; Rangnekar, V.M.
    Par-4 binds to topoisomerase 1 and attenuates its DNA relaxation activity (2008), Cancer Res., 68, 6190-6198.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.6.2.1

Inhibitors

Inhibitors Comment Organism Structure
glutathione S-transferase-Par-4
-
 Homo sapiens
glutathione S-transferase-Par-4
-
 Mus musculus
Par-4 tumor suppressor protein, prostate apoptosis response-4, binds to TOP1, via its leucine zipper domain, and prevents TOP1 interaction with the DNA Homo sapiens
Par-4 tumor suppressor protein, prostate apoptosis response-4, binds to TOP1, via its leucine zipper domain, and prevents TOP1 interaction with the DNA Mus musculus
Par-4-GFP
-
 Homo sapiens
Par-4-GFP
-
 Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell lung cancer cell Homo sapiens
-
BPH-1 cell human immortalized epithelial cells Homo sapiens
-
HEL cell human primary lung fibroblasts Homo sapiens
-
HeLa cell cervical cancer cell Homo sapiens
-
NIH-3T3 cell mouse immortalized fibroblasts Mus musculus
-
PC-3 cell prostate cancer cell Homo sapiens
-

Synonyms

Synonyms Comment Organism
Top1
-
 Mus musculus
Top1
-
 Homo sapiens
topoisomerase 1
-
 Mus musculus
topoisomerase 1
-
 Homo sapiens