Literature summary for 5.6.1.9 extracted from

Kim, J.; Pierik, A.; Buckel, W.
A complex of 2-Hydroxyisocaproyl-Coenzyme A dehydratase and its activator from clostridium difficile stabilized by aluminium tetrafluoride-adenosine diphosphate (2010), Chemphyschem, 11, 1307-1312 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
aluminium tetrafluoride-adenosine diphosphate	AlF4 x ADP traps the interaction of the activator HadI with the dehydratase by forming a stable complex containing 1.0 mol homodimeric activator, 1.0 mol heterodimeric dehydratase and 1.2 mol ADP. The complex formation proceeds much slower than the activation but in an almost irreversible manner. The isolated complex is devoid of any activity	Clostridioides difficile

Organism

Organism	UniProt	Comment	Textmining
Clostridioides difficile	Q5U925	-	-

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Release 2023.1 (January 2023)