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Literature summary for 5.6.1.3 extracted from

  • Nakagawa, T.; Tanaka, Y.; Matsuoka, E.; Kondo, S.; Okada, Y.; Noda, Y.; Kanai, Y.; Hirokawa, N.
    Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome (1997), Proc. Natl. Acad. Sci. USA, 94, 9654-9659.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
cDNA, PCR to identify new KIFs Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n Mus musculus
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Saccharomyces cerevisiae
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Xenopus laevis
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n Caenorhabditis elegans
-
ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Mus musculus
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Saccharomyces cerevisiae
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Xenopus laevis
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n Caenorhabditis elegans
-
GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans
-
-
-
Mus musculus
-
mouse
-
Saccharomyces cerevisiae
-
-
-
Xenopus laevis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Mus musculus

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Mus musculus
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Saccharomyces cerevisiae
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Xenopus laevis
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end) microtubular motor protein, involved in organelle movement, in mitosis and meiosis. In contrast to dynein, it moves along microtubules towards the plus end. Composed of two heavy (a) chains (110kDa) and two more light (b) chains (65-75 kDa). Also hydrolyzes GTP. Caenorhabditis elegans

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Mus musculus
-
heart
-
Mus musculus
-
hippocampus
-
Mus musculus
-
intestine
-
Mus musculus
-
kidney
-
Mus musculus
-
lung
-
Mus musculus
-
olfactory bulb
-
Mus musculus
-
spleen
-
Mus musculus
-
testis
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n
-
Mus musculus ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Saccharomyces cerevisiae ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Xenopus laevis ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
ATP + H2O + a kinesin associated with a microtubule at position n
-
Caenorhabditis elegans ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Mus musculus GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Saccharomyces cerevisiae GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Xenopus laevis GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?
GTP + H2O + a kinesin associated with a microtubule at position n
-
Caenorhabditis elegans GDP + phosphate a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
?

Synonyms

Synonyms Comment Organism
CELF56E3
-
Caenorhabditis elegans
Eg5
-
Xenopus laevis
KIF10
-
Mus musculus
KIF11
-
Mus musculus
KIF13A
-
Mus musculus
KIF13B
-
Mus musculus
KIF15
-
Mus musculus
KIF16A
-
Mus musculus
KIF16B
-
Mus musculus
KIF1A
-
Mus musculus
KIF1B
-
Mus musculus
KIF3A
-
Mus musculus
KIF3B
-
Mus musculus
KIF5
-
Mus musculus
KIF5A
-
Mus musculus
KIF5B
-
Mus musculus
KIF5C
-
Mus musculus
KIF6
-
Mus musculus
KIF7
-
Mus musculus
KIF8
-
Mus musculus
KIFC2
-
Mus musculus
KIP1
-
Saccharomyces cerevisiae
nKHC
-
Mus musculus