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Literature summary for 5.5.1.2 extracted from

  • Thatcher, D.R.; Cain, R.B.
    The kinetic properties of 3-carboxy-cis-cis-muconate cycloisomerase (1972), Biochem. J., 127, 33P-34P.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
Dicarboxylic acids saturated dicarboxylic acids with the exception of oxalate, are less inhibitory as the molecular weight increases. Compounds with two cis-carboxyl groups are much more inhibitory than the corresponding trans-isomers Aspergillus niger
Tricarboxylic acids
-
Aspergillus niger

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.052
-
2-carboxy-2,5-dihydro-5-oxofuran-2-acetate
-
Aspergillus niger

Organism

Organism UniProt Comment Textmining
Aspergillus niger
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-Carboxy-2,5-dihydro-5-oxofuran-2-acetate i.e. beta-carboxy-cis,cis-muconate Aspergillus niger cis-Butadiene-1,2,4-tricarboxylate i.e. gamma-carboxymuconolactone ?