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Literature summary for 5.4.99.43 extracted from

  • Ansmant, I.; Massenet, S.; Grosjean, H.; Motorin, Y.; Branlant, C.
    Identification of the Saccharomyces cerevisiae RNA:pseudouridine synthase responsible for formation of psi2819 in 21S mitochondrial ribosomal RNA (2000), Nucleic Acids Res., 28, 1941-1946.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
the selective uridine-pseudouridine conversion at position 2819 in mitochondrial 21S rRNA is restored when the deleted yeast strain is transformed by a plasmid expressing the wild-type YLR165c ORF Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
D71A inactive mutant enzyme Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
21S rRNA uridine2819 Saccharomyces cerevisiae pseudouridine2819 in mitochondrial 21S rRNA is not essential for cell viability 21S rRNA pseudouridine2819
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Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae Q06244
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
21S rRNA uridine2819
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 Saccharomyces cerevisiae 21S rRNA pseudouridine2819
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 ?
21S rRNA uridine2819 pseudouridine2819 in mitochondrial 21S rRNA is not essential for cell viability Saccharomyces cerevisiae 21S rRNA pseudouridine2819
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Synonyms

Synonyms Comment Organism
PUS5
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 Saccharomyces cerevisiae
Pus5p
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 Saccharomyces cerevisiae