Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ascorbic acid | required, D-ascorbate shows 80% of L-ascorbate in enhancing the reaction, cannot be replaced by other reducing agents | Mycobacterium tuberculosis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2.4 | - |
2-acetolactate | - |
Mycobacterium tuberculosis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-Acetolactate | Mycobacterium tuberculosis | enzyme of Ile-Val biosynthesis | ? | - |
? | |
2-Acetolactate | Mycobacterium tuberculosis H37Rv | enzyme of Ile-Val biosynthesis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
H37Rv | - |
Mycobacterium tuberculosis H37Rv | - |
H37Rv | - |
Storage Stability | Organism |
---|---|
90% loss of activity after 2 days, even when kept under frozen state | Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-aceto-2-hydroxybutanoate | - |
Mycobacterium tuberculosis | 3-hydroxy-3-methyl-2-oxopentanoate | - |
? | |
2-aceto-2-hydroxybutanoate | - |
Mycobacterium tuberculosis H37Rv | 3-hydroxy-3-methyl-2-oxopentanoate | - |
? | |
2-Acetolactate | - |
Mycobacterium tuberculosis | 3-Hydroxy-3-methyl-2-oxobutanoate | - |
? | |
2-Acetolactate | - |
Mycobacterium tuberculosis H37Rv | 3-Hydroxy-3-methyl-2-oxobutanoate | - |
? | |
2-Acetolactate | enzyme of Ile-Val biosynthesis | Mycobacterium tuberculosis | ? | - |
? | |
2-Acetolactate | enzyme of Ile-Val biosynthesis | Mycobacterium tuberculosis H37Rv | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Mycobacterium tuberculosis |