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Literature summary for 5.3.99.2 extracted from

  • Kumar, S.; Palaia, T.; Hall, C.; Ragolia, L.
    Role of lipocalin-type prostaglandin D2 synthase (L-PGDS) and its metabolite, prostaglandin D2, in preterm birth (2015), Prostaglandins Other Lipid Mediat., 118-119, 28-33 .
    View publication on PubMed
Search for more literature for 5.3.99.2

Application

Application Comment Organism
medicine elevated enzyme levels in the cervicovaginal secretions of women are a potential biomarker for preterm birth Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Prostaglandin H2 Mus musculus
-
 Prostaglandin D2
-
 ?
Prostaglandin H2 Homo sapiens
-
 Prostaglandin D2
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P41222
-
-
Mus musculus O09114
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cervicovaginal fluid
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Prostaglandin H2
-
 Mus musculus Prostaglandin D2
-
 ?
Prostaglandin H2
-
 Homo sapiens Prostaglandin D2
-
 ?

Synonyms

Synonyms Comment Organism
L-PGDS
-
 Mus musculus
L-PGDS
-
 Homo sapiens
lipocalin-type prostaglandin D2 synthase
-
 Mus musculus
lipocalin-type prostaglandin D2 synthase
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction the incidence of preterm birth is significantly reduced to 40% in enzyme-deficient knockout mice Mus musculus
physiological function the enzyme plays a role in lipopolysaccharide-induced preterm birth Homo sapiens