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Literature summary for 5.1.99.4 extracted from
- alpha-Methylacyl-coenzyme A racemase (AMACR, p504s) is a marker to distinguish malignant melanomas from dysplastic nevi and melanocytic nevi (2014), Tumour Biol., 35, 12015-12020 .
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | immunohistochemistry of cyclin-dependent kinase inhibitor 2A, AMACR, cyclin D1, and E-cadherin show no exclusive staining for nevi or melanomas. A significant overexpression of AMACR is found in malignant melanomas compared to benign nevi and is associated with an increased cyclin-dependent kinase inhibitor 2A staining | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| melanoma cell | - |
Homo sapiens | - |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | significant overexpression of AMACR is found in malignant melanomas compared to benign nevi | up |
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Release 2023.1 (January 2023)
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