Application | Comment | Organism |
---|---|---|
additional information | construction of a fusion between Deinococcus radiodurans bacteriophytochrome linked to Synechocystis sp. guanylate/adenylate cyclase. The construct shows low dark-state activity and high dynamic range that outperforms previous optogenetic tools in vitro | Synechocystis sp. PCC 6803 |
Crystallization (Comment) | Organism |
---|---|
fusion between Deinococcus radiodurans bacteriophytochrome linked to Synechocystis sp. guanylate/adenylate cyclase, to 2.35 A resolution. Light-induced conformational changes in the phytochrome destabilize the coiled-coil sensor-effector linker, which releases the cyclase regulatory element from an inhibited conformation, increasing cyclase activity of the artificial system | Synechocystis sp. PCC 6803 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Synechocystis sp. PCC 6803 | A0A068MZJ9 | - |
- |