Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Calmodulin | strong activation | Bordetella pertussis |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Bordetella pertussis |
General Stability | Organism |
---|---|
calmodulin stablizes CyaA | Bordetella pertussis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EGTA | freshly activated CyaA is inhibited by EGTA at low calmodulin concentrations | Bordetella pertussis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | Bordetella pertussis | - |
3',5'-cyclic AMP + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bordetella pertussis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant CyaA | Bordetella pertussis |
Storage Stability | Organism |
---|---|
-20°C, 8 M urea, no loss of activity | Bordetella pertussis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP | - |
Bordetella pertussis | 3',5'-cyclic AMP + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
adenylate cyclase toxin | - |
Bordetella pertussis |
CyaA | - |
Bordetella pertussis |