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Literature summary for 4.3.99.3 extracted from

  • Grell, T.A.J.; Bell, B.N.; Nguyen, C.; Dowling, D.P.; Bruender, N.A.; Bandarian, V.; Drennan, C.L.
    Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity (2018), Protein Sci., 28, 202-215 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Escherichia coli

Crystallization (Commentary)

Crystallization (Comment) Organism
the crystal structure of the enzyme is determined to 2.1 A resolution by multi-wavelength anomalous dispersion Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-carboxy-5,6,7,8-tetrahydropterin Escherichia coli
-
7-carboxy-7-carbaguanine + NH3
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-carboxy-5,6,7,8-tetrahydropterin
-
Escherichia coli 7-carboxy-7-carbaguanine + NH3
-
?

Synonyms

Synonyms Comment Organism
queE
-
Escherichia coli

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine S-adenosyl-L-methionine-dependent radical enzyme Escherichia coli