Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis(2-nitrobenzoate) | reversible with dithiothreitol, folate protects | Sus scrofa | |
folate | - |
Sus scrofa | |
HgCl2 | 0.05 mM, triethanolamine-HCl, pH 8.0, 95% loss of activity | Sus scrofa | |
additional information | - |
Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-formiminotetrahydrofolate | Sus scrofa | - |
? | - |
? | |
additional information | Sus scrofa | folate-dependent bifunctional enzyme formiminoglutamate: tetrahydrofolate formiminotransferase-formiminotetrahydrofolate cyclodeaminase catalyzes two sequential reactions of the histidine degradation pathway | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-formiminotetrahydrofolate | - |
Sus scrofa | 5,10-methenyltetrahydrofolate + NH3 | - |
? | |
5-formiminotetrahydrofolate | - |
Sus scrofa | ? | - |
? | |
additional information | folate-dependent bifunctional enzyme formiminoglutamate: tetrahydrofolate formiminotransferase-formiminotetrahydrofolate cyclodeaminase catalyzes two sequential reactions of the histidine degradation pathway | Sus scrofa | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
octamer | each of the eight subunits of the formiminotransferase-cyclodeaminase enzyme complex is a bifunctional polypeptide | Sus scrofa |