Literature summary for 4.2.3.6 extracted from

Tijerino, A.; Cardoza, R.E.; Moraga, J.; Malmierca, M.G.; Vicente, F.; Aleu, J.; Collado, I.G.; Gutierrez, S.; Monte, E.; Hermosa, R.
Overexpression of the trichodiene synthase gene tri5 increases trichodermin production and antimicrobial activity in Trichoderma brevicompactum (2011), Fungal Genet. Biol., 48, 285-296.

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Cloned(Commentary)

Cloned (Comment)	Organism
homologous overexpression in Trichoderma Brevicompactum	Trichoderma brevicompactum

Organism

Organism	UniProt	Comment	Textmining
Trichoderma brevicompactum	F4MJM0	-	-
Trichoderma brevicompactum IBT40841	F4MJM0	-	-

Synonyms

Synonyms	Comment	Organism
tri5	-	Trichoderma brevicompactum

Expression

Organism	Comment	Expression
Trichoderma brevicompactum	tri5 repression is observed in cultures supplemented with the antioxidants ferulic acid and tyrosol	down
Trichoderma brevicompactum	expression is up-regulated in media with glucose, H2O2 or glycerol	up

General Information

General Information	Comment	Organism
physiological function	tri5 overexpression leads to an increased production of trichodermin and tyrosol. Of these, only trichodermin has antifungal activity against Saccharomyces cerevisiae, Kluyveromyces marxianus, Candida albicans, Candida glabrata, Candida tropicalis and Aspergillus fumigatus	Trichoderma brevicompactum

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Release 2023.1 (January 2023)