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Literature summary for 4.2.3.118 extracted from

  • Wang, Z.; Xu, Y.; Shao, J.; Wang, J.; Li, R.
    Genes associated with 2-methylisoborneol biosynthesis in cyanobacteria: isolation, characterization, and expression in response to light (2011), PLoS One, 6, e18665.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.3.118

Organism

Organism UniProt Comment Textmining
Planktothricoides raciborskii G0YUP5 two adjacent genes, SAM-dependent methyltransferanse gene and monoterpene cyclase gene, are responsible for geranyl diphosphate methylation and subsequent cyclization to 2-methylisoborneol in cyanobacteria
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Pseudanabaena sp. G0YUP1 two adjacent genes, SAM-dependent methyltransferanse gene and monoterpene cyclase gene, are responsible for geranyl diphosphate methylation and subsequent cyclization to 2-methylisoborneol in cyanobacteria
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Pseudanabaena sp. dqh15 G0YUP1 two adjacent genes, SAM-dependent methyltransferanse gene and monoterpene cyclase gene, are responsible for geranyl diphosphate methylation and subsequent cyclization to 2-methylisoborneol in cyanobacteria
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(E)-2-methylgeranyl diphosphate + H2O
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 Pseudanabaena sp. 2-methylisoborneol + diphosphate
-
 ?
(E)-2-methylgeranyl diphosphate + H2O
-
 Planktothricoides raciborskii 2-methylisoborneol + diphosphate
-
 ?
(E)-2-methylgeranyl diphosphate + H2O
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 Pseudanabaena sp. dqh15 2-methylisoborneol + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
monoterpene cyclase
-
 Pseudanabaena sp.
monoterpene cyclase
-
 Planktothricoides raciborskii

Expression

Organism Comment Expression
Pseudanabaena sp. light is a crucial, but not the only, active regulatory factor for the transcription of 2-methylisoborneol synthesis genes. Under low light, there is a 30% increase in the transcription of methyltransferase and a 60% increase in methylisoborneol synthase transcription compared to controls within 3–12 h. Under high light intensity, however, transcription of these two genes decreases by 30% and 50%, respectively. Expression of both genes is inhibited when bacteria are cultured in the dark at 25°C for 72 h additional information
Planktothricoides raciborskii light is a crucial, but not the only, active regulatory factor for the transcription of 2-methylisoborneol synthesis genes. Under low light, there is a 30% increase in the transcription of methyltransferase and a 60% increase in methylisoborneol synthase transcription compared to controls within 3–12 h. Under high light intensity, however, transcription of these two genes decreases by 30% and 50%, respectively. Expression of both genes is inhibited when bacteria are cultured in the dark at 25°C for 72 h additional information