Application | Comment | Organism |
---|---|---|
drug development | siRNAs targeting mevalonate (diphospho) decarboxylase (MVD) are found to inhibit Dengue virus replication in a stable A549 subgenomic Renilla replicon cell line (Rluc-replicon) and in naive A549 cells after dengue type 2 (DEN-2) New Guinea C (NGC) live virus infection, knock down of mevalonate (diphospho) decarboxylase can inhibit dengue viral replication | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 5-diphosphomevalonate | Homo sapiens | - |
ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 5-diphosphomevalonate | - |
Homo sapiens | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
mevalonate diphospho decarboxylase | - |
Homo sapiens |
MVD | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | investigation of the role of mevalonate diphospho decarboxylase in viral replication | Homo sapiens |