Literature summary for 4.1.1.31 extracted from

Dick, M.; Erlenkamp, G.; Nguyen, G.T.T.; Foerster, K.; Groth, G.; Gohlke, H.
Pyrazolidine-3,5-dione-based inhibitors of phosphoenolpyruvate carboxylase as a new class of potential C (2017), FEBS Lett., 591, 3369-3377 .

Search for more literature for 4.1.1.31

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Flaveria pringlei
expression in Escherichia coli	Flaveria trinervia

Crystallization (Commentary)

Crystallization (Comment)	Organism
docking of compound (3-bromophenyl)-4-(3-hydroxybenzylidene)-pyrazolidine-3,5-dione into the binding sites of C3 and C4 PepC	Flaveria pringlei
docking of compound (3-bromophenyl)-4-(3-hydroxybenzylidene)-pyrazolidine-3,5-dione into the binding sites of C3 and C4 PepC	Flaveria trinervia

Inhibitors

Inhibitors	Comment	Organism	Structure
(3-bromophenyl)-4-(3-hydroxybenzylidene)-pyrazolidine-3,5-dione	compound has a selectivity factor of 16.6 for C4 plant PepC over C3 plant PepC	Flaveria pringlei
(3-bromophenyl)-4-(3-hydroxybenzylidene)-pyrazolidine-3,5-dione	compound has a selectivity factor of 16.6 over C3 PepC	Flaveria trinervia

Organism

Organism	UniProt	Comment	Textmining
Flaveria pringlei	Q01647	C3 plant	-
Flaveria trinervia	P30694	C4 plant	-

Synonyms

Synonyms	Comment	Organism
PpcA1	-	Flaveria pringlei

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.00196	-	pH 7.5, 25°C	Flaveria trinervia	(3-bromophenyl)-4-(3-hydroxybenzylidene)-pyrazolidine-3,5-dione
0.0326	-	pH 7.5, 25°C	Flaveria pringlei	(3-bromophenyl)-4-(3-hydroxybenzylidene)-pyrazolidine-3,5-dione

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Release 2023.1 (January 2023)