Literature summary for 4.1.1.17 extracted from

Maekitie, L.T.; Kanerva, K.; Polvikoski, T.; Paetau, A.; Andersson, L.C.
brain neurons express ornithine decarboxylase-activating antizyme inhibitor 2 with accumulation in Alzheimers disease (2010), Brain Pathol., 20, 571-580.

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Activating Compound

Activating Compound	Comment	Organism	Structure
antizyme inhibitor 2	-	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-ornithine	Homo sapiens	-	putrescine + CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-ornithine	-	Homo sapiens	putrescine + CO2	-	?

Synonyms

Synonyms	Comment	Organism
ODC	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
pyridoxal 5'-phosphate	-	Homo sapiens

General Information

General Information	Comment	Organism
metabolism	ornithine decarboxylase is the rate-limiting enzyme of polyamine synthesis	Homo sapiens

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Release 2023.1 (January 2023)