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Literature summary for 4.1.1.17 extracted from
- Biosynthetic and biodegradative ornithine and arginine decarboxylases from Escherichia coli (1983), Methods Enzymol., 94, 125-134.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 3.6 | - |
L-Orn | degradative ornithine decarboxylase | Escherichia coli |  |
| 5.6 | - |
L-Orn | biosynthetic ornithine decarboxylase | Escherichia coli | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 80000 | - |
2 * 80000, degradative ornithine decarboxylase | Escherichia coli |
| 81000 | - |
2 * 81000, biosynthetic ornithine decarboxylase | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| a biosynthetic ornithine decarboxylase and a degradative ornithine decarboxylase | Escherichia coli |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 99 | - |
biosynthetic ornithine decarboxylase | Escherichia coli |
| 130 | - |
degradative ornithine decarboxylase | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Orn | - |
Escherichia coli | Putrescine + CO2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 81000, biosynthetic ornithine decarboxylase | Escherichia coli |
| dimer | 2 * 80000, degradative ornithine decarboxylase | Escherichia coli |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| dODC | degradative ornithine decarboxylase | Escherichia coli |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Escherichia coli |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.9 | - |
degradative ornithine decarboxylase | Escherichia coli |
| 8.3 | - |
biosynthetic ornithine decarboxylase | Escherichia coli |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | cofactor | Escherichia coli | |
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Release 2023.1 (January 2023)
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