Literature summary for 3.6.5.4 extracted from

Kusters, R.; Lentzen, G.; Eppens, E.; van Geel, A.; van der Weijden, C.C.; Wintermeyer, W.; Luirink, J.
The functioning of the SRP receptor FtsY in protein-targeting in E.coli is correlated with its ability to bind and hydrolyse GTP (1995), FEBS Lett., 372, 253-258.

Search for more literature for 3.6.5.4

Application

Application	Comment	Organism
medicine	protein translocation across the endoplasmic reticulum	Escherichia coli

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Escherichia coli

Protein Variants

Protein Variants	Comment	Organism
additional information	FtsY mutated in the 4th GTP-binding consensus element displays reduced GTP-binding and -hydrolysis which correlates with a reduced ability to interact with SRP	Escherichia coli

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
GDP + H2O	Escherichia coli	-	GMP + phosphate	-	?
GTP + H2O	Escherichia coli	-	GDP + phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	SRP receptor FtsY	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GDP + H2O	-	Escherichia coli	GMP + phosphate	-	?
GTP + H2O	-	Escherichia coli	GDP + phosphate	-	?

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Release 2023.1 (January 2023)