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Literature summary for 3.6.5.3 extracted from

  • Rodnina, M.V.; Savelsbergh, A.; Katunin, V.I.; Wintermeyer, W.
    Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome (1997), Nature, 385, 37-41.
    View publication on PubMed
Search for more literature for 3.6.5.3

Application

Application Comment Organism
medicine protein biosynthesis Escherichia coli

Cloned(Commentary)

Cloned (Comment) Organism
-
 Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
GDP
-
 Escherichia coli
GDP gamma-S
-
 Escherichia coli
guanyl-5'yl-imidodiphosphate
-
 Escherichia coli
P3-1-(2-nitro)phenylethylguanosine 5'-O-triphosphate
-
 Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + H2O Escherichia coli
-
 GDP + phosphate
-
 ?
GTP + H2O Escherichia coli B / ATCC 11303
-
 GDP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
 elongation facor G ((EF)G)
-
Escherichia coli B / ATCC 11303
-
 elongation facor G ((EF)G)
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
 Escherichia coli GDP + phosphate
-
 ?
GTP + H2O
-
 Escherichia coli B / ATCC 11303 GDP + phosphate
-
 ?