Literature summary for 3.6.5.3 extracted from

Luchin, S.; Putzer, H.; Hershey, J.W.B.; Cenatiempo, Y.; Grunberg-Manago, M.; Laalami, S.
In vitro study of two dominant inhibitory GTPase mutants of Escherichia coli translation initiation factor IF2 (1999), J. Biol. Chem., 274, 6074-6079.

Search for more literature for 3.6.5.3

General Stability

General Stability	Organism
mutants lethal to E. coli	Escherichia coli

Inhibitors

Inhibitors	Comment	Organism	Structure
GDP	-	Escherichia coli

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0153	-	GTP	V400G	Escherichia coli
0.0247	-	GTP	H448E	Escherichia coli
0.03	-	GTP	wild type	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
GTP + H2O	Escherichia coli	-	GDP + phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	translation initiation factor IF2 mutants V400G and H448E, strain SL679R	-

Purification (Commentary)

Purification (Comment)	Organism
-	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GTP + H2O	-	Escherichia coli	GDP + phosphate	-	?

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Release 2023.1 (January 2023)