KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000069 | - |
Na+/K+-ATPase phosphoenzyme intermediate | cardiac muscle, phoshoenzyme intermediate of heart sarcolemma Na+,K+-ATPase | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Bos taurus | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Bos taurus | acylphosphatase increases the rate of Na+,K+-dependent ATP hydrolysis, acylphosphatase significantly stimulates the rate of ATP driven Na+ transport into sarcolemma vesicles: accelerrated hydrolysis of the phosphoenzyme may result in an enhanced activity of heart sarcolemma Na+,K+ pump, suggesting a potential role of acylphosphatase in the control of this active transport system | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
bovine | - |
Bos taurus | - |
two isoenzymatic forms: one prevalent in skeletal and cardiac muscle, the other in red blood cells | - |
Purification (Comment) | Organism |
---|---|
heart, cardiac muscle | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | cardiac muscle | Bos taurus | - |
muscle | cardiac muscle | Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
3650 | - |
heart, cardiac muscle | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(Ca2+-Mg2+)-ATPase phosphorylated intermediate + H2O | acylphosphorylated intermediates of Ca2+-ATPase from skeletal muscle sarcoplasmic reticulum and heart sarcolemma | Bos taurus | ? | - |
? | |
1,3-diphosphoglycerate + H2O | - |
Bos taurus | 3-phosphoglycerate + phosphate | - |
? | |
acylphosphate + H2O | specifically catalyzes the hydrolysis of the carboxyl-phosphate bond of various acylphosphates | Bos taurus | carboxylate + phosphate | - |
? | |
benzoyl phosphate + H2O | - |
Bos taurus | benzoate + phosphate | - |
? | |
carbamoyl phosphate + H2O | - |
Bos taurus | carbamate + phosphate | - |
? | |
additional information | acylphosphatase increases the rate of Na+,K+-dependent ATP hydrolysis, acylphosphatase significantly stimulates the rate of ATP driven Na+ transport into sarcolemma vesicles: accelerrated hydrolysis of the phosphoenzyme may result in an enhanced activity of heart sarcolemma Na+,K+ pump, suggesting a potential role of acylphosphatase in the control of this active transport system | Bos taurus | ? | - |
? | |
Na+/K+-ATPase phosphoenzyme intermediate + H2O | sarcolemma Na+,K+-ATPase phosphorylated intermediate | Bos taurus | ? | - |
? | |
Na+/K+-ATPase phosphoenzyme intermediate + H2O | acylphosphatase significantly enhances the rate of strophantidine-sensitive ATP hydrolysis, it uncouples erythrocyte membrane N+,K+ pump | Bos taurus | ? | - |
? | |
Na+/K+-ATPase phosphoenzyme intermediate + H2O | acylphosphatase hydrolyzes phosphoenzyme intermediate of heart sarcolemma Na+,K+-ATPase | Bos taurus | ? | - |
? | |
Na+/K+-ATPase phosphoenzyme intermediate + H2O | acylphosphatase increases the rate of Na+,K+-dependent ATP hydrolysis, acylphosphatase significantly stimulates the rate of ATP driven Na+ transport into sarcolemma vesicles: accelerated hydrolysis of the phosphoenzyme may result in an enhanced activity of heart sarcolemma Na+,K+ pump, suggesting a potential role of acylphosphatase in the control of this active transport system | Bos taurus | ? | - |
? | |
Na+/K+-ATPase phosphoenzyme intermediate + H2O | acylphosphorylated phosphoenzyme intermediate, enzyme has a high affinity for this substrate | Bos taurus | ? | - |
? | |
succinoyl phosphate + H2O | - |
Bos taurus | succinate + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
More | two isoenzymatic forms: one prevalent in skeletal and cardiac muscle named muscle type, the other in red blood cells named erythrocyte or common type, even if both isoforms are expressed in all tissues | Bos taurus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
100 | - |
2 h: heat inactivation | Bos taurus |