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Literature summary for 3.6.1.55 extracted from

  • Gao, T.; Gu, S.; Liu, F.; Li, L.; Wang, Z.; Yang, J.; Li, G.
    Investigation of MTH1 activity via mismatch-based DNA chain elongation (2016), Anal. Chim. Acta, 905, 66-71 .
    View publication on PubMed
Search for more literature for 3.6.1.55

Inhibitors

Inhibitors Comment Organism Structure
N4-cyclopropyl-6-(2,3-dichlorophenyl)pyrimidine-2,4-diamine i.e. TH588 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
8-oxo-dGTP + H2O Homo sapiens
-
 8-oxo-dGMP + diphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MCF-10A cell
-
 Homo sapiens
-
MCF-7 cell
-
 Homo sapiens
-
MDA-MB-231 cell
-
 Homo sapiens
-
T-47D cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
8-oxo-dGTP + H2O
-
 Homo sapiens 8-oxo-dGMP + diphosphate
-
 ?

Synonyms

Synonyms Comment Organism
8-oxo-dGTPase
-
 Homo sapiens
MTH1
-
 Homo sapiens
MutT homolog 1
-
 Homo sapiens