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Literature summary for 3.6.1.27 extracted from

  • El Ghachi, M.; Howe, N.; Huang, C.Y.; Olieric, V.; Warshamanage, R.; Touze, T.; Weichert, D.; Stansfeld, P.J.; Wang, M.; Kerff, F.; Caffrey, M.
    Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis (2018), Nat. Commun., 9, 1078 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.1.27

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli C43(DE3) cells Escherichia coli

Crystallization (Commentary)

Crystallization (Comment) Organism
using 40% (w/v) PEG 400, 0.3-0.5M ammonium citrate dibasic and 0.1M sodium citrate pH 5.0 Escherichia coli

Protein Variants

Protein Variants Comment Organism
S27A inactive Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Escherichia coli 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ the enzyme has a requirement for divalent cations and is most active with calcium Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
undecaprenyl diphosphate + H2O Escherichia coli
-
 undecaprenyl phosphate + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli P60932
-
-

Purification (Commentary)

Purification (Comment) Organism
HisTrap column chromatography and Superdex S200 gel filtration Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
farnesyl diphosphate + H2O
-
 Escherichia coli farnesyl phosphate + phosphate
-
 ?
undecaprenyl diphosphate + H2O
-
 Escherichia coli undecaprenyl phosphate + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
bacA
-
 Escherichia coli
undecaprenyl-pyrophosphate phosphatase
-
 Escherichia coli
UppP
-
 Escherichia coli