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Literature summary for 3.5.3.18 extracted from

  • MacAllister, R.J.; Parry, H.; Kimoto, M.; Ogawa, T.; Russell, R.J.; Hodson, H.; Whiteley, G.St.J.; Vallance, P.
    Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase (1996), Br. J. Pharmacol., 119, 1533-1540.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.3.18

Inhibitors

Inhibitors Comment Organism Structure
S-2-amino-4(3-methylguanidino)butanoic acid
-
 Homo sapiens
S-2-amino-4(3-methylguanidino)butanoic acid
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NG,NG-dimethyl-L-arginine + H2O Homo sapiens the enzyme plays a functional role in the regulation of nitric oxide synthase dimethylamine + L-citrulline
-
 ?
NG,NG-dimethyl-L-arginine + H2O Rattus norvegicus the enzyme plays a functional role in the regulation of nitric oxide synthase dimethylamine + L-citrulline
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
aorta
-
 Homo sapiens
-
aorta
-
 Rattus norvegicus
-
kidney
-
 Homo sapiens
-
kidney
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NG,NG-dimethyl-L-arginine + H2O
-
 Homo sapiens dimethylamine + L-citrulline
-
 ?
NG,NG-dimethyl-L-arginine + H2O
-
 Rattus norvegicus dimethylamine + L-citrulline
-
 ?
NG,NG-dimethyl-L-arginine + H2O the enzyme plays a functional role in the regulation of nitric oxide synthase Homo sapiens dimethylamine + L-citrulline
-
 ?
NG,NG-dimethyl-L-arginine + H2O the enzyme plays a functional role in the regulation of nitric oxide synthase Rattus norvegicus dimethylamine + L-citrulline
-
 ?