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Literature summary for 3.5.1.B15 extracted from
- In silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium (2015), J. Pharm. Sci. Res., 7, 416-419 .
No PubMed abstract available
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | in silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium | Mycobacterium tuberculosis variant bovis |
| additional information | in silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium | Mycobacterium kansasii |
| additional information | in silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium | Mycobacterium avium |
| additional information | in silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium | Mycolicibacterium smegmatis |
| additional information | in silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium | Mycobacteroides abscessus |
| additional information | in silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium | Mycobacterium marinum |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mycobacterium avium | P94914 | - |
- |
| Mycobacterium kansasii | O07691 | - |
- |
| Mycobacterium marinum | A0A3E2MTZ2 | - |
- |
| Mycobacterium tuberculosis variant bovis | U5TP36 | - |
- |
| Mycobacteroides abscessus | B1MLY1 | i.e. Mycobacterium abscessus | - |
| Mycobacteroides abscessus ATCC 19977 | B1MLY1 | i.e. Mycobacterium abscessus | - |
| Mycobacteroides abscessus CIP 104536 | B1MLY1 | i.e. Mycobacterium abscessus | - |
| Mycobacteroides abscessus DSM 44196 | B1MLY1 | i.e. Mycobacterium abscessus | - |
| Mycobacteroides abscessus JCM 13569 | B1MLY1 | i.e. Mycobacterium abscessus | - |
| Mycobacteroides abscessus NCTC 13031 | B1MLY1 | i.e. Mycobacterium abscessus | - |
| Mycobacteroides abscessus TMC 1543 | B1MLY1 | i.e. Mycobacterium abscessus | - |
| Mycolicibacterium smegmatis | Q9ZF59 | - |
- |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | enzyme structure comparison with the crystal structure of pyrazinamidase of Mycobacterium tuberculosis (PDB ID 3PL1) | Mycobacterium tuberculosis variant bovis |
| More | enzyme structure comparison with the crystal structure of pyrazinamidase of Mycobacterium tuberculosis (PDB ID 3PL1) | Mycobacterium kansasii |
| More | enzyme structure comparison with the crystal structure of pyrazinamidase of Mycobacterium tuberculosis (PDB ID 3PL1) | Mycobacterium avium |
| More | enzyme structure comparison with the crystal structure of pyrazinamidase of Mycobacterium tuberculosis (PDB ID 3PL1) | Mycolicibacterium smegmatis |
| More | enzyme structure comparison with the crystal structure of pyrazinamidase of Mycobacterium tuberculosis (PDB ID 3PL1) | Mycobacteroides abscessus |
| More | enzyme structure comparison with the crystal structure of pyrazinamidase of Mycobacterium tuberculosis (PDB ID 3PL1) | Mycobacterium marinum |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PncA | - |
Mycobacterium tuberculosis variant bovis |
| PncA | - |
Mycobacterium kansasii |
| PncA | - |
Mycobacterium avium |
| PncA | - |
Mycolicibacterium smegmatis |
| PncA | - |
Mycobacteroides abscessus |
| PncA | - |
Mycobacterium marinum |
| PZAse | - |
Mycobacterium tuberculosis variant bovis |
| PZAse | - |
Mycobacterium kansasii |
| PZAse | - |
Mycobacterium avium |
| PZAse | - |
Mycolicibacterium smegmatis |
| PZAse | - |
Mycobacteroides abscessus |
| PZAse | - |
Mycobacterium marinum |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | Mycobacterium abscessus is resistant to pyrazinamide due to the random mutations in the primary sequences of the pyrazinamidase. In silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium | Mycobacteroides abscessus |
| malfunction | Mycobacterium avium is resistant to pyrazinamide due to the random mutations in the primary sequences of the pyrazinamidase. In silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium | Mycobacterium avium |
| malfunction | Mycobacterium bovis is resistant to pyrazinamide due to the random mutations in the primary sequences of the pyrazinamidase. In silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium | Mycobacterium tuberculosis variant bovis |
| malfunction | Mycobacterium kansasii is resistant to pyrazinamide due to the random mutations in the primary sequences of the pyrazinamidase. In silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium | Mycobacterium kansasii |
| malfunction | Mycobacterium marinum is resistant to pyrazinamide due to the random mutations in the primary sequences of the pyrazinamidase. In silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium | Mycobacterium marinum |
| malfunction | Mycobacterium smegmatis is resistant to pyrazinamide due to the random mutations in the primary sequences of the pyrazinamidase. In silico structural characterizations of pyrazinamidase variants from various species of Mycobacterium | Mycolicibacterium smegmatis |
| additional information | the substrate binding site involves residues D8, F13, D49, K96, I133, A135, H137, and C138, binding sites architectures and GATE analysis, molecular dynamics simulations, overview | Mycobacterium tuberculosis variant bovis |
| additional information | the substrate binding site involves residues D8, F13, D49, K96, I133, A135, H137, and C138, binding sites architectures and GATE analysis, molecular dynamics simulations, overview | Mycobacterium kansasii |
| additional information | the substrate binding site involves residues D8, F13, D49, K96, I133, A135, H137, and C138, binding sites architectures and GATE analysis, molecular dynamics simulations, overview | Mycobacterium avium |
| additional information | the substrate binding site involves residues D8, F13, D49, K96, I133, A135, H137, and C138, binding sites architectures and GATE analysis, molecular dynamics simulations, overview | Mycolicibacterium smegmatis |
| additional information | the substrate binding site involves residues D8, F13, D49, K96, I133, A135, H137, and C138, binding sites architectures and GATE analysis, molecular dynamics simulations, overview | Mycobacteroides abscessus |
| additional information | the substrate binding site involves residues D8, F13, D49, K96, I133, A135, H137, and C138, binding sites architectures and GATE analysis, molecular dynamics simulations, overview | Mycobacterium marinum |
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