Literature summary for 3.5.1.88 extracted from

Liang, J.H.; Huo, X.K.; Cheng, Z.B.; Sun, C.P.; Zhao, J.C.; Kang, X.H.; Zhang, T.Y.; Chen, Z.J.; Yang, T.M.; Wu, Y.Y.; Deng, X.P.; Zhang, Y.X.
An indole diterpenoid isolated from the fungus Drechmeria sp. and its antimicrobial activity (2019), Nat. Prod. Res., 33, 2770-2776 .

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Inhibitors

Inhibitors	Comment	Organism	Structure
drechmerin I	an antibacterial compound, isolated from the fermentation broth of Drechmeria sp. strain SYPF 8335, which is isolated from the inside root of Panax notoginseng, from Wenshan district, Yunnan province of China. Compound structure determination by mass spectrometry and 1H and 13C NMR. Molecular docking in the active site of PDF from Staphylococcus aureus through the hydrogen bonds with Try88 and Arg143. Drechmerin I displays antimicrobial activity against Bacillus subtillis with an MIC value of 0.2 mg/ml	Staphylococcus aureus

Organism

Organism	UniProt	Comment	Textmining
Staphylococcus aureus	P68826	-	-
Staphylococcus aureus CGMCC 1.8721	P68826	-	-

Synonyms

Synonyms	Comment	Organism
PDF	-	Staphylococcus aureus

General Information

General Information	Comment	Organism
physiological function	enzyme PDF plays an important role in bacterial protein maturation, growth, and survival by degradation of the N-formyl group for the polypeptide	Staphylococcus aureus

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Release 2023.1 (January 2023)