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Literature summary for 3.5.1.48 extracted from
- Effect of N8-acetylspermidine deacetylase inhibition on the growth of L1210 cells (1999), Biochem. Pharmacol., 57, 1095-1103.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 7-[N-(3-aminopropyl)amino]heptan-2-one | stimulation of cell growth due to inhibition of N8-acetylspermidine deacetylase, maximum cell growth stimulation at 0.1 mM | Mus musculus |  |
| N8-Acetylspermidine | stimulation of cell growth due to inhibition of N8-acetylspremidine deacetylase, maximum cell growth stimulation above 1 mM | Mus musculus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Mus musculus | 5829 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
L1210 cells | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell culture | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N1-acetylspermidine + H2O | - |
Mus musculus | acetate + spermidine | - |
? | |
| N8-acetylspermidine + H2O | - |
Mus musculus | acetate + spermidine | - |
? | |
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