Literature summary for 3.4.99.B1 extracted from

Ma , C.; Yang, Y.; Xu, L.; Tu, W.; Chen, F.; Wang, J.
Rce1 suppresses invasion and metastasis of hepatocellular carcinoma via epithelial-mesenchymal transition induced by the TGF-beta1/H-Ras signaling pathway (2020), J. Cell. Physiol., 235, 2506-2520 .

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Application

Application	Comment	Organism
medicine	expression of Rce1 is significantly decreased in hepatocellular carcinoma compared with noncancerous tissues, while H-Ras expression is increased in the tumor. The expression of both is a close association with the differentiation and tumor-node-metastasis stage of the tumor. Rce1 is an independent prognostic indicator. Lower expression of Rce1 facilitates epithelial-mesenchymalctransition and promotes the invasion and metastasis of hepatocellular carcinoma	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9Y256	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
hepatoma cell	-	Homo sapiens	-
liver	-	Homo sapiens	-

General Information

General Information	Comment	Organism
physiological function	Rce1 can bind with farnesyltransferase beta	Homo sapiens

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Release 2023.1 (January 2023)