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Literature summary for 3.4.99.B1 extracted from
- Divergent roles of CAAX motif-signaled posttranslational modifications in the regulation and subcellular localization of Ral GTPases (2015), J. Biol. Chem., 290, 22851-61 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P57791 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fibroblast | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| small GTPase RalA + H2O | - |
Mus musculus | ? | - |
? |  |
| small GTPase RalB + H2O | - |
Mus musculus | ? | - |
? | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | both Ras-like small GTPases RalA and RalB require Ras converting CAAX endopeptidase 1 (RCE1) for association with the plasma membrane, albeit not with endomembranes, and loss of RCE1 causes mislocalization as well as sustained activation of both RalA and RalB | Mus musculus |
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Release 2023.1 (January 2023)
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