Literature summary for 3.4.24.B9 extracted from

Cong, L.; Jia, J.
Promoter polymorphisms which regulate ADAM9 transcription are protective against sporadic Alzheimers disease (2009), Neurobiol. Aging, 32, 54-62.

Search for more literature for 3.4.24.B9

Cloned(Commentary)

Cloned (Comment)	Organism
ADAM9 gene, DNA and amino acid sequence determination and analysis, screening and analysis of the promoter region, expression of mutants iin SH-SY5Y and HeLa cells	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	screening of the ADAM9 gene promoter region identifies four polymorphisms: -542C/T (rs10105311), -600A/C (rs7840270), -963A/G (rs6991968) and -1314T/C (rs7006414), genotyping and phenotyping, overview. Both -963G/-1314C and -963A/-1314C have 1.5-1.8fold and 1.4-1.7fold higher transcriptional activity, respectively, than -963A/-1314T	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	female and male sporadic Alzheimer's disease patients	-

Synonyms

Synonyms	Comment	Organism
ADAM9	-	Homo sapiens

General Information

General Information	Comment	Organism
additional information	promoter polymorphisms, which regulate ADAM9 transcription, are protective against sporadic Alzheimer's disease	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)