Crystallization (Comment) | Organism |
---|---|
recombinant enzyme, hanging-drop vapour diffusion method, 20 mM Tris-HCl, pH 7.3, 5 mM CaCl2, 300 mM NaCl, addition of 1 M ammonium sulfate solution, pH 9.0, equilibrated against ammonium sulfate at 1.2 M, 20°C, 1 week, X-ray structure determination at 2.7 A resolution and analyis of the C-terminal haemopexin-like domain | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
protein + H2O | Homo sapiens | enzyme is involved in human breast cancer pathology and in arthritic processes | peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P45452 | recombinant procollagnase expressed in NSO mouse myeloma cells and secreted to the medium | - |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
protein + H2O | - |
Homo sapiens | peptides | - |
? | |
protein + H2O | enzyme is involved in human breast cancer pathology and in arthritic processes | Homo sapiens | peptides | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | structure and peptide organization, three-dimensional modeling | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
M10.013 | Merops-ID | Homo sapiens |
matrix metalloproteinase-13 | - |
Homo sapiens |
MMP-13 | - |
Homo sapiens |