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Literature summary for 3.4.24.B3 extracted from

  • Gonzalez de Vega, R.; Clases, D.; Fernandez-Sanchez, M.L.; Eiro, N.; Gonzalez, L.O.; Vizoso, F.J.; Doble, P.A.; Sanz-Medel, A.
    MMP-11 as a biomarker for metastatic breast cancer by immunohistochemical-assisted imaging mass spectrometry (2019), Anal. Bioanal. Chem., 411, 639-646 .
    View publication on PubMed

Application

Application Comment Organism
diagnostics MMP-11 is a biomarker for metastatic breast cancer by immunohistochemical-assisted imaging mass spectrometry Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ MMP-11 is a zinc-dependent endopeptidase, Zn2+ is integral to MMP-11 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P24347
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Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell samples from patients with histologically confirmed diagnosis of early invasive breast cancers of ductal types, expression of MMP-11 is increased and more heterogeneous in metastatic specimens compared to non-metastatic tumour samples, quantitative expression and mapping of the cancer biomarker MMP-11 in human breast cancer tissue sections, overview Homo sapiens
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additional information development and evaluation of a gold nanoparticle-based immunoassay for measuring MMP-11 expression and mapping its distribution pattern in breast cancer tissues, overview Homo sapiens
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Synonyms

Synonyms Comment Organism
MMP-11
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Homo sapiens

General Information

General Information Comment Organism
physiological function enzyme MMP-11 is involved in breast cancer initiation, progress and metastases development, MMP-11 plays a key role in the progression of cancer Homo sapiens