Application | Comment | Organism |
---|---|---|
diagnostics | MMP-11 is a biomarker for metastatic breast cancer by immunohistochemical-assisted imaging mass spectrometry | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | MMP-11 is a zinc-dependent endopeptidase, Zn2+ is integral to MMP-11 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P24347 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast cancer cell | samples from patients with histologically confirmed diagnosis of early invasive breast cancers of ductal types, expression of MMP-11 is increased and more heterogeneous in metastatic specimens compared to non-metastatic tumour samples, quantitative expression and mapping of the cancer biomarker MMP-11 in human breast cancer tissue sections, overview | Homo sapiens | - |
additional information | development and evaluation of a gold nanoparticle-based immunoassay for measuring MMP-11 expression and mapping its distribution pattern in breast cancer tissues, overview | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
MMP-11 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | enzyme MMP-11 is involved in breast cancer initiation, progress and metastases development, MMP-11 plays a key role in the progression of cancer | Homo sapiens |