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Literature summary for 3.4.24.B15 extracted from

  • Bowe, A.E.; Finnegan, R.; Jan de Beur, S.M.; Cho, J.; Levine, M.A.; Kumar, R.; Schiavi, S.C.
    FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate (2001), Biochem. Biophys. Res. Commun., 284, 977-981.
    View publication on PubMed
Search for more literature for 3.4.24.B15

Cloned(Commentary)

Cloned (Comment) Organism
expression as V5-epitope tagged enzyme in an in vitro rabbit reticulocyte lysate system Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protein + H2O Homo sapiens enzyme is involved in pathology of oncogenic osteomalacia, X-linked hypophosphatemia, and autosomal dominant hypophosphatemic rickets peptides
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
oncogenic osteomalacia cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protein + H2O
-
 Homo sapiens peptides
-
 ?
protein + H2O enzyme is involved in pathology of oncogenic osteomalacia, X-linked hypophosphatemia, and autosomal dominant hypophosphatemic rickets Homo sapiens peptides
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 ?
protein FGF-23 + H2O recombinant wild-type substrate, but not the recombinant mutant FGF-23(R179Q) Homo sapiens ?
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 ?

Synonyms

Synonyms Comment Organism
M13.091 Merops-ID Homo sapiens
PHEX
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens