Literature summary for 3.4.24.B12 extracted from

Aydos, O.S.; Yukselten, Y.; Ozkavukcu, S.; Sunguroglu, A.; Aydos, K.
ADAMTS1 and ADAMTS5 metalloproteases produced by Sertoli cells a potential diagnostic marker in azoospermia (2019), Syst. Biol. Reprod. Med., 65, 29-38 .

Search for more literature for 3.4.24.B12

Application

Application	Comment	Organism
medicine	the enzyme is a diagnostic marker in azoospermia	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q8TE58	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
semen	-	Homo sapiens	-
Sertoli cell	-	Homo sapiens	-

Subunits

Subunits	Comment	Organism
?	x * 75000, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
a disintegrin and metalloproteinase with thrombospondin motifs 5	-	Homo sapiens
ADAMTS5	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	the enzyme is expressed 2.1fold less in Sertoli cells of individuals with nonobstructive azoospermia than those of control individuals with obstructive azoospermia	down

General Information

General Information	Comment	Organism
malfunction	insufficiency of enzyme expression in Sertoli cells may have an important role in the etiology of male infertility	Homo sapiens

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Release 2023.1 (January 2023)