Cloned (Comment) | Organism |
---|---|
expressed in HEK-293 cells | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
von Willebrand factor + H2O | Homo sapiens | ADAMTS13 cleaves the bond Tyr842-Met843 within the A2 domain, i.e. Tyr1605-Met1606 in von Willebrand factor UniProt Id P04275 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood plasma | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Collagen + H2O | - |
Homo sapiens | ? | - |
? | |
additional information | PNGase-treated von Willebrand factor is more succeptible to proteolysis by ADAMTS13 and binds with increased affinity | Homo sapiens | ? | - |
? | |
von Willebrand factor + H2O | ADAMTS13 cleaves the bond Tyr842-Met843 within the A2 domain, i.e. Tyr1605-Met1606 in von Willebrand factor UniProt Id P04275 | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADAMTS13 | - |
Homo sapiens |
von Willebrand factor cleaving protease | - |
Homo sapiens |
VWF cleaving protease | - |
Homo sapiens |